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Updated: Apr 30, 2020

By Caroline Zanelli


Collagen makes up 30% of our body’s totally protein, its’ crucial for:

  • Mobile joints

  • Stable bones

  • Healthy muscle

  • Strong ligaments and tendons

  • Smooth skin

  • Glossy hair,

  • Healthy fingernails.


Collagenous protein makes up nearly 70% of cartilage mass. Optimized specific collagen peptides such as FORTIGEL have been proven to activate the growth of new cartilage by stimulating cells helping to make the joints smooth and mobile.

The effectiveness of FORTIGEL has been scientifically research in 20 human intervention studies with more than 3,000 patients proving the health benefit of collagen supplementation in joint cartilage, bones, ligaments and tendons (4).

Scientific substantiated claims with regard to Joint Health:

Counteracts the progressive loss of cartilage tissue

Promotes joint health through a natural physiological pathway

Stimulates collagen Type II synthesis

Stimulates hyaluronic acid synthesis

Supports mobility

Maintains cartilage

Helps reduce exercise induced pain

Supports new formation of cartilage tissue mass (4)


When specific collagen peptides such as VERISOL are administered orally they influence skin collagen metabolism directly from the inside, it increases the skin moisture and delays the formation of wrinkles (1).

Scientific substantiated claims with regard to skin:

Increases skin firmness and elasticity (1)

Reduces wrinkles and fine lines (2)

Stimulate metabolism of collagen, proteoglycans and elastin in the (deeper) skin

Enhances skin smoothness and reduces the appearance of fine surface lines (3)

Offers nutrients for healthy skin

Rejuvenate skin from within (1)


Specific collagen peptides such as Fortibone stimulate bone cells to increase the synthesis of bone compartments such as collagen. They have a signalling effect on osteoblast to counterbalance the collagen degradation in the extracellular bone matrix, which is essential for the framework of bone mineralization. Collagen peptides also influence the degeneration processes in bones by reducing osteoclast activity, this results in a considerably higher synthesis of collagenous bone matrix (5)

Various clinical and pre-clinical research confirm bone health effect for collagen peptides.

Scientific substantiated claims with regard to Bone Health:

Stimulating bone matrix synthesis and mineralization

Supports bone mass increase and helps to decrease bone matrix degradation

Supports reduced bone degradation processes in osteopenic and osteoporotic patients (5)

For further information about collagen and collagen supplementation talk to our nutritionist Caroline Zanelli!


1. Proksch E, Segger D, Degwert J, Schunck M, Zague V, Oesser S (2013) Oral Supplements of Specific Collagen Peptides Has Beneficial Effects on Human Skin Physiology: A Double blind Placebo-Controlled Study, Skin Pharmacology Physiology

2. Proksch E, Schunck M, Zague V, Segger D, Degwert J, Oesser (2013) Oral Intake of Specific Bioactive Collagen Peptides Reduces Skin Wrinkles and Increases Dermal Matrix Synthesis, Skin Pharmacol Physiology

3. Schunck M, Zague V, Oesser S, Proksch E, (2015) Dietary Supplementation with Specific Collagen Peptides Has a Body Mass Index-Dependant Benefical Effect on Cellulit Morphology. Journal of Medicinal Food

4. Oesser S, Raabe, A, Schunck M,. (2007) Collagen Metabolism of Human Osteoarthritic Articular Cartilage as Modulated by Bovine Collagen Hydrolysates, Osteoarthritis Cartilage

5. Alves RD, Demmers JA, Bezstarosti K, van der Eerden BC, Verhaar JA, Eiijken M, van Leeuwen JP, (2011) Unraveling the human bone microenvironment beyond the classical extracellular matrix protects: a human bone protein library. J Proteome Res.


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